ⓘ Carbonic anhydrase 9

                                     

ⓘ Carbonic anhydrase 9

Carbonic anhydrase IX is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase isoforms found in humans and is a transmembrane dimeric metalloenzyme with an extracellular active site that facilitates acid secretion in the gastrointestinal tract. CA IX is overexpressed in many types of cancer including clear cell renal cell carcinoma as well as carcinomas of the cervix, breast and lung where it promotes tumor growth by enhancing tumor acidosis.

                                     
  • and the dissociated ions of carbonic acid i.e. bicarbonate and hydrogen ions The active site of most carbonic anhydrases contains a zinc ion. They are
  • Carbonic anhydrase 5B, mitochondrial is an enzyme that in humans is encoded by the CA5B gene. Carbonic anhydrases CAs are a large family of zinc metalloenzymes
  • Carbonic anhydrase 3 is an enzyme that in humans is encoded by the CA3 gene. Carbonic anhydrase III CAIII is a member of a multigene family at least
  • Carbonic anhydrase 4 is an enzyme that in humans is encoded by the CA4 gene. Carbonic anhydrases CAs are a large family of zinc metalloenzymes that catalyze
  • Carbonic anhydrase 7 CA7 is an enzyme that in humans is encoded by the CA7 gene. Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze
  • Carbonic anhydrase 5A, mitochondrial is a protein that in humans is encoded by the CA5A gene. Carbonic anhydrases CAs are a family of zinc metalloenzymes
  • Carbonic anhydrase 12 is an enzyme that in humans is encoded by the CA12 gene. Carbonic anhydrases CAs are a large family of zinc metalloenzymes that
  • Carbonic anhydrase 13 is a protein that in humans is encoded by the CA13 gene. Carbonic anhydrases CAs are a family of zinc metalloenzymes that catalyze
  • Carbonic anhydrase 14 is an enzyme that in humans is encoded by the CA14 gene. Carbonic anhydrases CAs are a large family of zinc metalloenzymes that
  • Carbonic anhydrase II gene name CA2 is one of sixteen forms of human α carbonic anhydrases Carbonic anhydrase catalyzes reversible hydration of carbon