ⓘ Exosome component 2

                                     

ⓘ Exosome component 2

Mammalian mRNAs contain AU-rich elements AREs within their three prime untranslated regions. In yeast, 3-prime-to-5-prime mRNA degradation is mediated by the exosome, a multisubunit particle. EXOSC2 which is homologous to the yeast Rrp4 protein is a component of the human exosome.