ⓘ MTAP

                                     

ⓘ MTAP

S-methyl-5-thioadenosine phosphorylase is an enzyme that in humans is encoded by the MTAP gene.

This gene encodes an enzyme that plays an important role in the metabolism of polyamines essential for salvation, as adenine and methionine. The encoded enzyme is deficient in many cancers because this gene by the tumor suppressor P16 gene is deleted together. Several alternative spliced variants of the transcript have been described for this gene but their full length nature is unknown.