ⓘ GBGT1

                                     

ⓘ GBGT1

Globoside alpha-1.3-N-acetylgalactosaminyltransferase 1 is an enzyme that in humans is encoded by the GBGT1 gene.

This gene encodes a member of the histo-blood group ABO gene family that encodes glycosyltransferases with related but distinct substrate specificity. This protein plays an important role in the synthesis of Forssman glycolipid FG, a member of the globoseries glycolipid family. Human cells usually do not produce the FG, but to produce the precursor glycolipids, globotriaosylceramide and globoside. This protein may be involved in the tropism and binding of pathogenic organisms.